Tag archives: biophysics
By Hamish Johnston
There are still 10 days to go until Halloween, but some physicists can’t resist getting into the spirit a bit early. Over at Symmetry, Kathryn Jepsen suggests a few scary physics films that would make for a spooky movie night on 31 October. They’re not actually real films, but rather a series of posters dreamt up at Chicago’s Sandbox Studio in collaboration with the illustrator Ana Kova. My favourite is Poltergauss (right), because trying to understand magnetism is terrifying.
By Matin Durrani
The cover story in the September 2016 issue of Physics World magazine – now live in the Physics World app for mobile and desktop – reveals the fascinating new field of “crowd breath research”, which can even shed light on how cinema audiences react during the changing scenes in a movie. You can read the article here on physicsworld.com too.
The September issue also shows how to do crystallography without crystals, explains how first data from the Gaia spacecraft could revolutionize astronomy (see the above video for more on that), and contains one physics teacher’s fascinating story about what she did to change her school’s gender balance.
Don’t miss either reader feedback on the potential impact of Britain leaving the EU on physics or Robert P Crease’s Critical Point column on why science denial is one of the most important issues in the US presidential campaign.
By Tushna Commissariat
After a long trip in the US – attending the APS March meeting and visiting both the Maryland campus of the National Institute for Standards and Technology, as well as the Brookhaven National Laboratory in New York – I finally made my way back home yesterday. As I flew out of New York, I was reminded of my visit to NIST’s Surface and Trace Chemical Analysis Group, where researchers develop a variety of ways to detect contraband substances at airports and other public locations. While the team looks into a variety of ways to detect trace residues of banned substances such as drugs or explosives that may be found on people or objects – from mass spectroscopy to thermal desorption to vapour-sampling – my favourite was their canine research that led them to create a 3D-printed dog’s nose!
By Tushna Commissariat in Baltimore, Maryland, US
You may think that a simple occurrence such as a tree shedding its leaves or an everyday activity such as knitting or ribbon-curling does not involve a great deal of physics, but you would be wrong. In a press session here at the APS March meeting entitled “The physics of everyday life”, three different groups of researches talked about the unexpectedly complex physical principles that govern all of the above mentioned instances.
Sunny Jung of the Bio-Inspired Fluid Lab at Virginia Tech in the US studies the shapes of different leaves and the thickness of their “petioles” or stalks – both of which determine the stresses a leaf can withstand on a windy day and what happens when it ultimately falls. Jung’s team studies this because leaves are actually very good at withstanding all kinds of stress and strain without buckling – something that could be applied to large man-made industrial objects such as suspended road-signs.
The researchers found that slender leaves are more likely to bend under high winds, whereas a flat leaf is more likely to twist at the stem before falling. They also discovered that the length of the stalk is determined by the size of the leaf, with larger leaves needing longer stems so that sunlight can cover more of their surface area.
By Tushna Commissariat
Don’t tell the kids just yet, but becoming Spider-Man, even after being bitten by a radioactive spider, is looking less and less likely for us humans – we are just too big. The latest work, done by researchers at the University of Cambridge in the UK, has shown that gecko-sized is pretty much the largest you can be if you realistically want to scale up walls with adhesive pads. Any bigger, and most of your surface area would need to be covered in large sticky pads to pull off the gravity-defying walk. Indeed, the team estimates that roughly 40% of an average human being’s total body surface would need to be sticky – this means a whopping 80% of your front would be covered in adhesive pads.
By Hamish Johnston at the CAP Congress in Edmonton, Alberta
One promising route to understanding the causes of Alzheimer’s disease (AD) – and hopefully finding a cure – is the study of how and why proteins in the brain sometimes form neurotoxic plaques. These plaques are disc-like structures that are about 50 µm in diameter and made from polypeptides. Their presence in the grey matter of the brain is strongly associated with AD and some other neurological conditions, but why they form and why they cause dementia are both not understood.
By Margaret Harris at the AAAS meeting in San Jose
“Restoration of sight to the blind” is a brave claim, one with an almost Biblical ring to it. For Daniel Palanker, though, it is beginning to look as if it is an achievable goal. A medical physicist at the University of Stanford, Palanker has developed a prosthetic vision system that replaces damaged photoreceptors in the retina with an array of tiny photodiodes. When infrared images are projected onto this array, the photodiodes convert the light pulses into electrical signals, which are then picked up by the neurons behind the retina and transmitted to the brain. The result is an artificially induced visual response that, while not as good as normal vision, could nevertheless provide “highly functional restoration of sight” to people with conditions such as retinitis pigmentosa or age-related macular degeneration (AMD).
By Margaret Harris in San Francisco
The International Year of Light is a global celebration, but right now, it’s definitely got its heart in San Francisco. For the past five days, experts in optics, lasers and biomedical imaging have been converging on the “city by the bay” for the annual Photonics West conference, and I’ve joined them in order to learn more about the hot topics in optical science.
By Susan Curtis in Baltimore, US
At the 59th annual meeting of the Biophysical Society today, Rommie Amaro of the University of California, San Diego, highlighted the power of computational methods to speed up the discovery of new drugs to treat diseases as diverse as flu and cancer. Amaro focused on a recent project conducted while she was at the University of California, Irvine, to identify compounds that could play a vital role in future anti-cancer drugs by helping to reactive a molecule called p53 that is known to inhibit the formation of cancer cells.
By Susan Curtis in Baltimore, US
I’m in Baltimore this week for the 59th annual meeting of the Biophysical Society. The field of biophysics has grown rapidly in recent years as physics-based techniques have opened up new ways to study and understand biological processes, but with my limited knowledge of biology I was nervous that I would feel a little out of my depth.
The first talk of the “New and Notable” symposium helped to allay my fears. Michelle Wang is a physicist at Cornell University in the US who exploits optical techniques to trap and manipulate biomolecules. While established methods can only trap a single biomolecule at a time, Wang and her colleagues have pioneered the use of nanophotonic structures that can trap multiple biomolecules in a standing wave created within an optical waveguide.
“Our optical-trapping innovation reduces bench-top optics to a small device on a chip,” Wang told physicsworld.com when the team first reported their so-called nanophotonic standing-wave array trap last year. Since then, Wang and her colleagues have been working to integrate fluorescent markers with the nanophotonic trap to track the position of individual biomolecules, and have also been experimenting with optical waveguide materials other than silicon to improve performance and enable new applications.